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heart failure

Practice targeted AMC-style multiple-choice questions on heart failure.

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A 68-year-old woman with a history of hypertension and heart failure is being treated with an ACE inhibitor. Her recent blood tests show a potassium level of 5.8 mmol/L. Which of the following is the most appropriate initial step in managing her hyperkalemia?

A. Prescribe a loop diuretic such as furosemide
B. Administer intravenous calcium gluconate
C. Immediately commence haemodialysis
D. Review and potentially reduce or discontinue the ACE inhibitor
E. Administer intravenous insulin and glucose
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A 72-year-old man with fatigue and a past myocardial infarction at 55 is breathless on stairs, has a 3 kg weight gain, and ankle marks. What is his likely NYHA functional class for chronic heart failure?

A. NYHA Class 3
B. NYHA Class 2
C. NYHA Class 4
D. NYHA Class 1
E. Not enough information to classify.
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A 58-year-old man with a history of hypertension and left ventricular systolic dysfunction (LVSD) is being treated with an ACE inhibitor. His blood pressure is well-controlled, but he develops a persistent, dry cough that is affecting his sleep and quality of life. What is the most appropriate next step in management?

A. Add a cough suppressant
B. Switch to an angiotensin II receptor blocker (ARB)
C. Add a diuretic
D. Discontinue the ACE inhibitor and start a beta-blocker
E. Reduce the dose of the ACE inhibitor
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A 68-year-old woman with a history of hypertension and heart failure is admitted to the hospital with increasing shortness of breath and peripheral edema. She is currently taking furosemide 40mg daily. Her blood tests reveal the following: Na+ 130 mmol/L (135-145 mmol/L), K+ 3.1 mmol/L (3.5-5.0 mmol/L), Cl- 95 mmol/L (98-107 mmol/L), HCO3- 32 mmol/L (22-29 mmol/L). What is the most appropriate initial management?

A. Administer intravenous normal saline and continue furosemide at the same dose.
B. Administer an ACE inhibitor and monitor sodium levels.
C. Administer intravenous sodium bicarbonate and increase the dose of furosemide.
D. Hold furosemide, administer intravenous potassium chloride, and restrict free water intake.
E. Administer intravenous calcium gluconate and monitor potassium levels.
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A 72-year-old man with a history of chronic heart failure with reduced ejection fraction (HFrEF) and atrial fibrillation presents to the cardiology clinic for routine follow-up. He reports increased fatigue and occasional palpitations but denies chest pain or syncope. His current medications include lisinopril, carvedilol, furosemide, and digoxin. His blood pressure is 110/70 mmHg, heart rate is 78 bpm, and he has mild peripheral edema. Recent laboratory tests show a serum creatinine of 1.2 mg/dL and potassium of 4.5 mmol/L. An echocardiogram shows an ejection fraction of 35%. Considering his current medication regimen and clinical status, which of the following is the most appropriate next step in his pharmacological management?

A. Increase the dose of carvedilol
B. Initiate ivabradine
C. Start warfarin for anticoagulation
D. Switch lisinopril to sacubitril/valsartan
E. Add spironolactone
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A 68-year-old woman with a history of heart failure presents to the emergency department with increasing shortness of breath and lower extremity edema. She has been taking furosemide 40mg daily for the past year. Her blood pressure is 110/70 mmHg, heart rate is 90 bpm, and respiratory rate is 24 breaths/min. An ECG shows flattened T waves and prominent U waves. Which of the following is the most likely electrolyte abnormality contributing to her presentation?

A. Hypomagnesemia
B. Hypercalcemia
C. Hyperkalemia
D. Hypokalemia
E. Hyponatremia
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An 80-year-old man with known severe COPD and stable ischaemic heart disease presents to the emergency department with a 2-day history of worsening shortness of breath, increased cough productive of yellow sputum, and ankle swelling. He is usually independent but now struggles to walk across a room. On examination: Alert but distressed. BP 130/85 mmHg, HR 110 bpm, RR 28 breaths/min, Temp 37.8°C, SpO2 88% on room air. Chest examination reveals diffuse wheezes and crackles bilaterally, reduced air entry at the bases. JVP is elevated to 5 cm above the sternal angle. Mild pitting edema to the knees. ECG shows sinus tachycardia, no acute ischaemic changes. Chest X-ray shows hyperinflation, flattened diaphragms, increased bronchial markings, and mild interstitial prominence. Given this presentation, what is the most appropriate initial management step?

A. Administer controlled oxygen therapy aiming for SpO2 88-92% and nebulised bronchodilators.
B. Administer intravenous broad-spectrum antibiotics.
C. Perform urgent echocardiogram.
D. Administer intravenous furosemide.
E. Administer high-flow oxygen via non-rebreather mask.
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A 72-year-old man with a history of heart failure and hypertension is admitted to the hospital with pneumonia. His medications include furosemide, ramipril, and digoxin. On day 3 of admission, he develops new-onset polymorphic ventricular tachycardia (Torsades de Pointes). An ECG shows a QTc interval of 580 ms. Which of the following is the MOST likely contributing factor to his arrhythmia?

A. Pneumonia-related hypoxia
B. Digoxin toxicity
C. Underlying structural heart disease
D. Ramipril-induced bradycardia
E. Electrolyte imbalance secondary to furosemide
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A 65-year-old man with a history of hypertension and ischemic heart disease presents to the emergency department with worsening shortness of breath, orthopnea, and peripheral edema. On examination, he has elevated jugular venous pressure, bilateral basal crackles, and pitting edema in the lower limbs. An echocardiogram shows an ejection fraction of 35%. What is the most appropriate initial management step for this patient?

A. Initiate digoxin therapy
B. Perform coronary angiography
C. Start oral beta-blockers
D. Administer intravenous furosemide
E. Prescribe oral ACE inhibitors
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A 68-year-old man with a history of hypertension and coronary artery disease presents to the emergency department with worsening shortness of breath and fatigue over the past week. On examination, he has elevated jugular venous pressure, bilateral lung crackles, and peripheral edema. An echocardiogram reveals reduced ejection fraction and dilated ventricles. Which of the following best explains the pathophysiological mechanism leading to his symptoms?

A. Increased peripheral resistance leading to left ventricular hypertrophy
B. Decreased venous return causing systemic hypotension
C. Enhanced myocardial contractility resulting in fluid retention
D. Decreased cardiac output leading to activation of the renin-angiotensin-aldosterone system
E. Increased cardiac output causing pulmonary congestion
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A 70-year-old woman with a history of hypertension presents with fatigue, shortness of breath, and bilateral leg swelling. Echocardiography shows an ejection fraction of 30%. What is the most appropriate first-line treatment?

A. Calcium channel blocker
B. Nitrate therapy
C. ACE inhibitor and beta-blocker
D. Digoxin
E. Diuretic therapy alone
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A 78-year-old woman with a history of heart failure (reduced ejection fraction), type 2 diabetes, and recent hospitalisation for pneumonia presents to her GP with increasing fatigue and a single episode of dizziness leading to a fall without loss of consciousness. Her current medications are Digoxin 125 mcg daily, Furosemide 40 mg daily, Ramipril 5 mg daily, Metformin 500 mg BD, and Amoxicillin 500 mg TDS (started 5 days ago for pneumonia). An ECG in clinic shows sinus rhythm, rate 70 bpm, and a QTc of 530 ms. An ECG from 6 months prior had a QTc of 440 ms. Recent laboratory tests show Na 138 mmol/L, K 4.2 mmol/L, Mg 0.9 mmol/L, Ca 2.3 mmol/L, Creatinine 90 µmol/L, and Digoxin level 1.1 ng/mL. Considering the clinical context and investigations, which of the following is the most likely significant contributor to the observed QTc prolongation?

A. Ramipril
B. Underlying heart failure
C. Amoxicillin
D. Digoxin
E. Furosemide
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A 72-year-old man with fatigue, a past myocardial infarction at age 55, breathlessness on stairs, and ankle marks has an LVEF < 40% on echocardiogram. Which of the following medications is known to improve outcomes in Heart Failure with Reduced Ejection Fraction (HFrEF)?

A. Digoxin
B. Verapamil
C. Frusemide
D. Amlodipine
E. Eplerenone
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A 70-year-old man with a history of hypertension and heart failure is being managed with an ACE inhibitor. He presents to the emergency department complaining of dizziness, especially when standing up. His blood pressure is 90/60 mmHg, and his other vital signs are stable. Which of the following is the most appropriate initial step in managing this patient?

A. Order an ECG to rule out cardiac arrhythmia
B. Prescribe compression stockings
C. Review and potentially reduce the dose of the ACE inhibitor
D. Administer an intravenous bolus of normal saline
E. Start fludrocortisone
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